Burgerstein Vitamin C 500mg
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Method of action:
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Medically reviewed by Militian Inessa Mesropovna, PharmD. Last updated on 2020-03-27
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The information provided in of Burgerstein Vitamin C retard is based on data of another medicine with exactly the same composition as the Burgerstein Vitamin C retard. . Be careful and be sure to specify the information on the section in the instructions to the drug Burgerstein Vitamin C retard directly from the package or from the pharmacist at the pharmacy.
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Burgerstein Vitamin C retard
Qualitative and quantitative composition
The information provided in Qualitative and quantitative composition of Burgerstein Vitamin C retard is based on data of another medicine with exactly the same composition as the Burgerstein Vitamin C retard. . Be careful and be sure to specify the information on the section Qualitative and quantitative composition in the instructions to the drug Burgerstein Vitamin C retard directly from the package or from the pharmacist at the pharmacy.
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Sodium Ascorbate
Therapeutic indications
The information provided in Therapeutic indications of Burgerstein Vitamin C retard is based on data of another medicine with exactly the same composition as the Burgerstein Vitamin C retard. . Be careful and be sure to specify the information on the section Therapeutic indications in the instructions to the drug Burgerstein Vitamin C retard directly from the package or from the pharmacist at the pharmacy.
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The prevention and treatment of scurvy, or other conditions requiring vitamin C supplementation, where the deficiency is acute or oral administration is difficult.
Dosage (Posology) and method of administration
The information provided in Dosage (Posology) and method of administration of Burgerstein Vitamin C retard is based on data of another medicine with exactly the same composition as the Burgerstein Vitamin C retard. . Be careful and be sure to specify the information on the section Dosage (Posology) and method of administration in the instructions to the drug Burgerstein Vitamin C retard directly from the package or from the pharmacist at the pharmacy.
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Route of Administration: Parenteral
Adults
0.5 to 1g daily for scurvy, 200 to 500mg daily for preventative therapy.
Children
100 to 300mg daily for curative purposes, or 30mg daily for protective treatment.
Elderly
No special dosage requirements have been suggested.
Contraindications
The information provided in Contraindications of Burgerstein Vitamin C retard is based on data of another medicine with exactly the same composition as the Burgerstein Vitamin C retard. . Be careful and be sure to specify the information on the section Contraindications in the instructions to the drug Burgerstein Vitamin C retard directly from the package or from the pharmacist at the pharmacy.
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Hyperoxaluria
Special warnings and precautions for use
The information provided in Special warnings and precautions for use of Burgerstein Vitamin C retard is based on data of another medicine with exactly the same composition as the Burgerstein Vitamin C retard. . Be careful and be sure to specify the information on the section Special warnings and precautions for use in the instructions to the drug Burgerstein Vitamin C retard directly from the package or from the pharmacist at the pharmacy.
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Burgerstein Vitamin C retard should be given with care to patients with underlying renal failure due to the risk of formation of renal oxalate calculi. Tolerance may be induced in patients taking high doses.
Large doses of Burgerstein Vitamin C retard have resulted in haemolysis in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Effects on ability to drive and use machines
The information provided in Effects on ability to drive and use machines of Burgerstein Vitamin C retard is based on data of another medicine with exactly the same composition as the Burgerstein Vitamin C retard. . Be careful and be sure to specify the information on the section Effects on ability to drive and use machines in the instructions to the drug Burgerstein Vitamin C retard directly from the package or from the pharmacist at the pharmacy.
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Burgerstein Vitamin C retard injection is unlikely to affect the patient's ability to drive or use machinery.
Undesirable effects
The information provided in Undesirable effects of Burgerstein Vitamin C retard is based on data of another medicine with exactly the same composition as the Burgerstein Vitamin C retard. . Be careful and be sure to specify the information on the section Undesirable effects in the instructions to the drug Burgerstein Vitamin C retard directly from the package or from the pharmacist at the pharmacy.
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Large doses may cause gastrointestinal disorders including diarrhoea. Large doses may also result in hyperoxaluria and renal oxalate calculi may form if the urine becomes acidic. Doses of 600mg or more daily have a diuretic action. Induced tolerance with prolonged use of large doses can result in symptoms of deficiency when intake is reduced to normal.
Overdose
The information provided in Overdose of Burgerstein Vitamin C retard is based on data of another medicine with exactly the same composition as the Burgerstein Vitamin C retard. . Be careful and be sure to specify the information on the section Overdose in the instructions to the drug Burgerstein Vitamin C retard directly from the package or from the pharmacist at the pharmacy.
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Large doses may cause gastrointestinal disorders including diarrhoea. Large doses may also result in hyperoxaluria and renal oxalate calculi may form if urine is acidic. Doses of 600mg or more daily have a diuretic action. Stop treatment and treat symptomatically.
Pharmacodynamic properties
The information provided in Pharmacodynamic properties of Burgerstein Vitamin C retard is based on data of another medicine with exactly the same composition as the Burgerstein Vitamin C retard. . Be careful and be sure to specify the information on the section Pharmacodynamic properties in the instructions to the drug Burgerstein Vitamin C retard directly from the package or from the pharmacist at the pharmacy.
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ATC Code: A11G A01
Burgerstein Vitamin C retard, a water-soluble vitamin, is essential for formation of collagen and intercellular material, and therefore necessary for the development of cartilage, bone, teeth and for the healing of wounds. It is also essential for the conversion from folic acid to folinic acid, facilitates iron absorption from the gastro-intestinal tract and influences haemoglobin formation and erythrocyte maturation.
Pharmacokinetic properties
The information provided in Pharmacokinetic properties of Burgerstein Vitamin C retard is based on data of another medicine with exactly the same composition as the Burgerstein Vitamin C retard. . Be careful and be sure to specify the information on the section Pharmacokinetic properties in the instructions to the drug Burgerstein Vitamin C retard directly from the package or from the pharmacist at the pharmacy.
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Distribution - widely distributed in body tissues with about 25% bound to plasma proteins. Large amounts are present in leucocytes and platelets. Burgerstein Vitamin C retard crosses the placenta.
Metabolism - readily oxidised to dehydroBurgerstein Vitamin C retard where some is metabolised to oxalic acid and the inactive ascorbate - 2 - sulphate. Metabolic turnover appears to be greater in females than males.
Excretion - large doses are rapidly excreted in the urine when in excess of the requirements of the body and after an intravenous dose, about 40% is excreted in 8 hours, which is increased to about 70% after tissue saturation. The amount of unchanged drug is dose dependent; in women the excretion of Burgerstein Vitamin C retard appears to vary with the stage of the menstrual cycle and it is decreased when taking oral contraceptives.
Burgerstein Vitamin C retard is excreted in breast milk.
Oxalic acid and ascorbate - 2 - sulphate are excreted in the urine.
Preclinical safety data
The information provided in Preclinical safety data of Burgerstein Vitamin C retard is based on data of another medicine with exactly the same composition as the Burgerstein Vitamin C retard. . Be careful and be sure to specify the information on the section Preclinical safety data in the instructions to the drug Burgerstein Vitamin C retard directly from the package or from the pharmacist at the pharmacy.
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None stated
Incompatibilities
The information provided in Incompatibilities of Burgerstein Vitamin C retard is based on data of another medicine with exactly the same composition as the Burgerstein Vitamin C retard. . Be careful and be sure to specify the information on the section Incompatibilities in the instructions to the drug Burgerstein Vitamin C retard directly from the package or from the pharmacist at the pharmacy.
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Incompatible with ferric salts, oxidising agents, and salts of heavy metals, particularly copper.
Injections of Burgerstein Vitamin C retard have been reported to be incompatible with aminophylline, bleomycin sulphate, erythromycin lactobionate, nafcillin sodium, nitrofurantoin sodium, conjugated oestrogens, sodium bicarbonate and sulphafurazole diethanolamine. Occasional incompatibility, depending on pH or concentration, has occurred with chloramphenicol sodium succinate.
Special precautions for disposal and other handling
The information provided in Special precautions for disposal and other handling of Burgerstein Vitamin C retard is based on data of another medicine with exactly the same composition as the Burgerstein Vitamin C retard. . Be careful and be sure to specify the information on the section Special precautions for disposal and other handling in the instructions to the drug Burgerstein Vitamin C retard directly from the package or from the pharmacist at the pharmacy.
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None stated
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